adults have renal failure4
of the US population use low-dose aspirin for CVD prevention5
adults have liver disease6
adults will be diagnosed with cancer in their lifetime7
|
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A
Active
|
P
Passive
|
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Function independently of the patient’s ability to generate clotting factors to achieve hemostasis |
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Effective regardless of coagulation status |
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Effective across a wide range of bleeding |
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Bleeding Severity
*Based on preclinical data. Results may not correlate to performance in humans.
Flowables(thrombin + gelatin)
Fibrin sealant
Stand-alone thrombin
Advanced patcheswith PEG or fibrin sealants
Oxidized Cellulose
Collagens
Powders
Gelatin Sponges
Polysaccharide Spheres
*Preclinical data. Results may not correlate to performance in humans.
1. Stokes ME, et al. BMC Health Services Research 2011;11:135; 2. Salive ME. Epidemiol Rev 2013;35:75–83; 3. Mather M, et al. Aging in the United States. Population Bulletin 70, 2015. Available at: https://www.prb.org/wp-content/uploads/2016/01/aging-us-population-bulletin-1.pdf (accessed January 2020); 4. Centers for Disease Control and Prevention. Chronic Kidney Disease Surveillance System. Available at: https://nccd.cdc.gov/ckd/default.aspx (Accessed January 2020); 5. Stuntz M, et al. Prev Med Rep. 2017;5:183–186; 6. Centers for Disease Control and Prevention. Chronic Liver Disease and Cirrhosis. Available at: https://www.cdc.gov/nchs/fastats/liver-disease.htm (Accessed January 2020); 7. American Cancer Society. Facts & Figures 2019: US Cancer Death Rate has Dropped 27% in 25 Years, Jan 2019. Available at: https://www.cancer.org/latest-news/facts-and-figures-2019.html (Accessed January 2020); 8. Corral M, et al. Clinicoecon Outcomes Res 2015;7:409–21; 9. Slezak P, et al. J Invest Surg 2020; ePub ahead of print; 10. Nasso G, et al. Ann Thorac Surg 2009;88:1520–6; 11. Bracey A, et al. Ann Thorac Surg 2017;104:353–60; 12. Tackett SM, et al. J Med Econ 2014;17:670–6.